Denver County Clostridium difficile Trends and Associated Risk Factors 2011-2013

A retrospective chart review studied 892 Denver  Clostridium difficile  cases from 2011 through 2013 with incident stool specimen reported to the state health department. Cases were stratified by epidemiologic classification (HFCO, CO-HCFA or CO-CA) and analyzed for associations with demographic and risk factors. Denver CDI incidence rate increased from 129/100,000 residents in 2011 to 139/100,000 residents in 2013. During the study period, the presence of underlying morbidities and antibiotic exposure increased in all onset types.