Synthesis of 1, 2, 4-triazines, XII: New synthesis of 1, 2, 4-triazines with a functional group in the 6-position

Abstract 6-Acyl- ( 15 , 17 ) and 6-ethoxycarbonyl-5-substituted 1,2,4-triazines ( 11 ) were prepared by refluxing acylhydrazones (10, 14) or N,N-dimethylaminomethylenehydrazones ( 16 ) with ammonium acetate in acetic acid. NMR-studies confirmed the high regio selectivity of this procedure.