Inflamación granulomatosa peneana por inyección de sustancia extraña

Liquid silicone has been utilized as a medical material for decades. In urology, it has been used to enhance the girth of the penis through subcutaneous tissue injection. Said practice can produce a granulomatous inflammatory reaction with local deformity, resulting in a foreign body reaction called “siliconoma”. We present herein the case of a patient with penile lipogranuloma secondary to the injection of an unknown substance that required surgical treatment to excise the affected tissue and cover the defect with cutaneous grafts. It is our opinion that such an enhancement practice is not justified, given its possible catastrophic consequences.