A clinical analysis of benign diseases in the oral cavity
1984
Odontogenic keratocyst was introduced by Philipsen in 1956 and described some of its clinical, radiological and microscopic features. This cyst has a thin wall characterized by keratinizing epithelium. Odontogenic keratocysts were of interest to the oral surgeon because of their tendency to recur and because they may possess a neoplastic potential. A total of 20 odontogenic keratocyst cases in the Second Department of Oral Surgery, Kyushu Dental College Hospital, during 1979 to 1983, were clinically analysed. The following results were obtained:1. A series of 20 cases of odontogenic keratocyst were reported. Its incidence was seen in 0.3% of outpatients, in 8% of cystic disease and in 16.7% of odontogenic cyst.2. The odontogenic keratocyst in the majority of the 20 cases was located on the mandible, especially on the mandibular molar region and ascending ramus.3. Of the 20 cases, 15 (75%) were between 20 and 40 years of age (average 37.7 years) and half were males.4. The complaint most commonly reported was a bony, hard swelling. The recorded known duration showed a range of 6 months.5. 14 cases (70%) had radiologically unilocular appearance and 6 cases (30%) were multilocular appearance. 8 cases (40%) appeared as dentigerous cyst, in that the crown of an unerupted tooth was associated with the cyst cavity. In only 2 cases (10%), there was radiological evidence of resorption of the roots.6. This series was found histopathologically to be: in 8 cases (40%) of the odontogenic keratocyst, there was rete peg, and in 6 cases (30%), there was inflammation of connective tissue in the cyst wall. In 5 cases (25%), the basal cell layers showed budding-like proliferations suggestive of dental lamina structure. On only 2 cases (10%), there was a daughter cyst, and in only 1 case (5%) there was a small island of odontogenic epithelium.7. Treatment was performed mostly by total enucleation of the lesion.
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