Monogenic and Polygenic Contributions to Atrial Fibrillation Risk

Seung Hoan Choi,Sean J. Jurgens,Lu-Chen Weng,James P. Pirruccello,Carolina Roselli,Mark Chaffin,Christina J.-Y. Lee,Amelia Weber Hall,Amit Khera,Kathryn L. Lunetta,Steven A. Lubitz,Patrick T. Ellinor

Monogenic and Polygenic Contributions to Atrial Fibrillation Risk

2020

Seung Hoan Choi
Sean J. Jurgens
Lu-Chen Weng
James P. Pirruccello
Carolina Roselli
Mark Chaffin
Christina J.-Y. Lee
Amelia Weber Hall
Amit Khera
Kathryn L. Lunetta
Steven A. Lubitz
Patrick T. Ellinor

Rationale: Genome-wide association studies have identified over 100 genetic loci for atrial fibrillation (AF); recent work described an association between loss-of-function (LOF) variants in TTN an...

Keywords:

Locus (genetics)
Atrial fibrillation
Internal medicine
Diabetes mellitus
Biology
Population
Cardiology
Genetic association
Exome
Bioinformatics

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