Multi-drug resistant Pseudomonas aeruginosa isolates from Kermanshah hospitals

Background and Objective : The antibiotic resistance of pathogenic strains of P. aeruginosa is increasing and the treatment of Pseudomonas infections has become a medical concern. We aimed to test the antibiotic resistance among pathogenic isolates of P. aeruginosa . Materials: In this study 96 pathogenic strains of P. aeruginosa were collected from Imam Khomainy and Imam Reza hospitals in Kermanshah during 2011-2012. After identification, the antibiotic susceptibility of bacteria was carried out using disc diffusion method according to the Clinical and Laboratory Standards Institute recommendations. Results: The average age of patients was 34.7±22.5 year. Among isolates, 28 (29.1%) were resistant to all antibiotics, but only 10(10.4%) were sensitive to all antibiotics. The highest sensitivity was for aminoglycosides in particular gentamicin and the lowest sensitivity was for carbenicillin and aztreonam. Conclusion: The results of this study warn for the increasing of multidrug and extensively drug resistant strains in Kermanshah city. Therefore the continuous surveillance for antibiotic resistance can help to better understand the antibiotic susceptibility of this opportunistic pathogen to the current drugs. The results of this study suggest that from anti- Pseudomonas penicillins, piperacillin/tazobactam and from aminoglycosides, gentamicin and amikacin, are effective drugs and can be used for treatment of Pseudomonas infections.