Effect of Colchicine on the Stress-Type ACTH Release in Rats

The adenohypophysis is an endocrine gland that cumulates the synthesized hormones in membrane—bound organelles—secretory granules. Secretion of cell products is a complex process involving the packaging of cell secretions in membrane to form vesicles, the transport of the vesicles to the cell membrane and their release into the extracellular space.