GREEN SYNTHESIS OF BENZOXAZOLE DERIVATIES AND THEIR CHARACTERIZATION

Synthesis of Benzoxazolederivatives by simple condensation of 2-aminophenol and different aromatic amd aliphatic acid in ethanol as solvent in presence of NH4Cl as catalyst at 80-90oC. It give very good yield and the process was totally fallow green path and economically viable. Benzoxazolederivatives have many medicinal and other biological properties.. The characterization of newly synthesized compounds was made by chemical properties, elemental analysis and FT-IR,1H-NMR and Mass Spectra. The advantage of this method is extremely mild reaction conditions, short reaction time, high yield, simple experimental technique and compliance with green chemistry protocols.