One-pot synthesis of β -amino esters by recyclable magnetic organocatalyst-catalysed Mannich-type reaction

L-cysteine supported on an iron oxide magnetic nanoparticle was prepared by a facile and simple method. The catalyst was effectively applied to the one-pot synthesis of β-amino esters in moderate to good yield. Moreover, the magnetic organocatalyst could be readily recovered and reused up to five times without significant loss of its catalytic activity.