A bio-oriented anthranilic acid catalyzed synthesis of quinazolin-8 (4H)-one derivatives: Evaluation by green chemistry metrics

ABSTRACTAn environmental friendly synthetic route has been investigated for the synthesis of quinazolin-8 (4H)-one derivatives in the presence of anthranilic acid as a catalyst. The zwitter ion formed in course of reaction may a play key role in the desired transformations leading good to excellent yields. Evaluation of the present protocol by green chemistry metrics demonstrated that it is highly efficient and eco-compatible.