Synthesis, Characterization and Antibacterial Activity of Metal Complexes from Schiff Base

Due to invention of new diseases, the need of antibiotics is increasing day by day. As many of the Schiff base transition metal complexes possess antibacterial activity we have planned to prepare some Schiff base transition metal complexes and to assess their antimicrobial activity. So, we have prepared the Schiff base by condensing Salicylaldehyde and Thiourea. Using this as the ligand, transition metal complexes have been prepared with the metal ions Ni(II), Fe(II), Hg(II), Zn(II) and Cd(II). The ligand as well as the complexes were characterized by using experimental techniques like Elemental Analysis, UV-Vis, FT-IR, and 1H NMR. The structure is proposed. The antibacterial activity of the complexes have been assessed against the bacteria Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Ceftazidime, Salmonella typhi “H”, Klebsiella Aerogenes, Micrococci, Proteus vulgaris, and Bacillus subtilis. Some of the complexes show antibacterial activity.