Dominant negative effect on male fertility and sperm maturation by haploinsufficiency of ELOVL2 in mouse

Damir Zadravec,Petr Tvrdik,Hervé Guillou,Richard P. Haslam,Tsutomu Kobayashi,Johnathan A. Napier,Mario R. Capecchi,Anders Jacobsson

Dominant negative effect on male fertility and sperm maturation by haploinsufficiency of ELOVL2 in mouse

2010

Damir Zadravec
Petr Tvrdik
Hervé Guillou
Richard P. Haslam
Tsutomu Kobayashi
Johnathan A. Napier
Mario R. Capecchi
Anders Jacobsson

ELOVL2 is a member of the mammalian microsomal enzyme family (ELOVL) involved in the elongation of very long-chain fatty acids (VLCFAs) including polyunsaturated fatty acids (PUFAs). Specifically, ...

Keywords:

Sperm
Microsome
Enzyme
Fertility
Polyunsaturated fatty acid
Genetics
Biochemistry
Biology
Haploinsufficiency
enzyme family
Internal medicine
Endocrinology
male fertility
dominant negative

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