Pharmaceutical Equivalent Study of Losartan Potassium Formulation available in Karachi, Pakistan

The purpose of this study is to check pharmaceutical equivalence of altered brands of Losartan Potassium tablets available in Karachi, Pakistan. Two different brands of Losartan Potassium tablets (50 mg) were investigated in the study. Five Quality Control (QC) parameters: Weight variation, thickness test, hardness, friability and disintegration tests were carried out as specified by BP/USP (British Pharmacopoeia and United State Pharmacopoeia). The result of study revealed that all above mentioned tests are in accordance with BP/USP. Both brands of Losartan Potassium tablets are Pharmaceutical Equivalent.