Successful multimodal treatment of Paecilomyces lilacinus infection in a dog

A four-year-old English springer spaniel was presented with a nine-month history of immune-mediated thrombocytopenia and one-month history of ulcerative skin lesions. Histopathology of the skin lesions identified intralesional fungal yeasts and hyphae. Definitive diagnosis was achieved via culture, which identified the organism as Paecilomyces lilacinus . This report describes the successful management of the first UK documented case of canine P lilacinus infection following tapering of immunosuppressive treatment and combined antifungal therapy.