Impact of molecular (DNA) testing on determination of parentage.

Abstract Objective.—To examine changes in parentage testing practices since the introduction of DNA polymorphisms. Methods.—Comparison of data from American Association of Blood Banks (AABB) annual questionnaires and the responses of participants to AABB–College of American Pathologists proficiency test panels. Results.—DNA polymorphisms have led to a complete change in the technical methods used by parentage testing laboratories. Conclusions.—The widespread use of DNA methods has increased the power of the information routinely provided to the courts in cases of disputed paternity, to agencies needing information about relatedness, and to the individuals who are tested.