Mifepristone composition lyophilized tablet and preparation method thereof

The invention provides a mifepristone composition lyophilized tablet and a preparation method thereof, and relates to the technical field of medicine and medicine production. The tablet is prepared from mifepristone, starch and sucrose, wherein the starch and sucrose are used as auxiliary materials, and common corn starch is subjected to heat process, so that adhesion and disintegration effects of the starch in a tablet can be improved, and the moldability of the tablet can be improved; and only starch and sucrose are needed in the mifepristone composition lyophilized tablet. According to the preparation method, a two-decreasing two-increasing lyophilizing process is adopted for the mifepristone composition lyophilized tablet, the moldability of the tablet can be better by means of twice cooling and twice heating, the solubility of the tablet can be improved, and the bioavailability of the tablet can be improved; the tablet is capable of overcoming the defect of conventional mifepristone tablets and reducing the types and usage of auxiliaries in the mifepristone tablets, is high in solubility and high in bioavailability, and can be used for guaranteeing the curative effect and safety of clinical administration.