MicroRNA regulating stanniocalcin-1 is a metastasis and dissemination promoting factor in glioblastoma

Junichi Sakata,Takashi Sasayama,Kazuhiro Tanaka,Hiroaki Nagashima,Mitsutoshi Nakada,Hirotomo Tanaka,Naoya Hashimoto,Naoki Kagawa,Manabu Kinoshita,Satoshi Nakamizo,Masahiro Maeyama,Masamitsu Nishihara,Kohkichi Hosoda,Eiji Kohmura

MicroRNA regulating stanniocalcin-1 is a metastasis and dissemination promoting factor in glioblastoma

2019

Junichi Sakata
Takashi Sasayama
Kazuhiro Tanaka
Hiroaki Nagashima
Mitsutoshi Nakada
Hirotomo Tanaka
Naoya Hashimoto
Naoki Kagawa
Manabu Kinoshita
Satoshi Nakamizo
Masahiro Maeyama
Masamitsu Nishihara
Kohkichi Hosoda
Eiji Kohmura

Background MicroRNAs (miRs) regulate many biological processes, such as invasion, angiogenesis, and metastasis. Glioblastoma (GBM) patients with metastasis/metastatic dissemination have a very poor prognosis; therefore, inhibiting metastasis/metastatic dissemination has become an important therapeutic strategy for GBM treatment.

Keywords:

Cancer research
Glioblastoma
Stanniocalcin
Angiogenesis
Metastasis
Biomarker (medicine)
microRNA
STC1
Medicine
Autocrine signalling
Gene knockdown
Survival analysis

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