Extracellular HMGB1 Modulates Glutamate Metabolism Associated with Kainic Acid-Induced Epilepsy-Like Hyperactivity in Primary Rat Neural Cells

Yuji Kaneko,Colleen Pappas,Teresita Malapira,Fernando Ĺ. Vale,Naoki Tajiri,Cesar V. Borlongan

Extracellular HMGB1 Modulates Glutamate Metabolism Associated with Kainic Acid-Induced Epilepsy-Like Hyperactivity in Primary Rat Neural Cells

2017

Yuji Kaneko
Colleen Pappas
Teresita Malapira
Fernando Ĺ. Vale
Naoki Tajiri
Cesar V. Borlongan

Background/Aims: Neuroinflammatory processes have been implicated in the pathophysiology of seizure/epilepsy. High mobility group box 1 (HMGB1), a non-histone DNA

Keywords:

Biochemistry
Pathophysiology
Epilepsy
High-mobility group
HMGB1
Extracellular
Diabetes mellitus
Kainic acid
Glutamate receptor
Biology

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