Benzofuran—Chalcone Hybrids as Potential Multifunctional Agents Against Alzheimer′s Disease: Synthesis and in vivo Studies with Transgenic Caenorhabditis elegans.

Koneni V. Sashidhara,Ram K. Modukuri,Pooja Jadiya,Ranga Prasad Dodda,Manoj Kumar,Balasubramaniam Sridhar,Vikash Kumar,Rizwanul Haque,Mohammad Imran Siddiqi,Aamir Nazir

Benzofuran—Chalcone Hybrids as Potential Multifunctional Agents Against Alzheimer′s Disease: Synthesis and in vivo Studies with Transgenic Caenorhabditis elegans.

2015

Koneni V. Sashidhara
Ram K. Modukuri
Pooja Jadiya
Ranga Prasad Dodda
Manoj Kumar
Balasubramaniam Sridhar
Vikash Kumar
Rizwanul Haque
Mohammad Imran Siddiqi
Aamir Nazir

A series of novel hybrid compounds incorporating benzofuran and chalcone fragments (V) are designed, synthesized and evaluated as potential agents against Alzheimer′s disease.

Keywords:

Benzofuran
Hybrid
Caenorhabditis elegans
Chalcone
In vivo
Biochemistry
Chemistry
Organic chemistry
Transgene

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