Assessment of Pain Sensitivity in Patients With Chronic Low Back Pain and Association With HTR2A Gene Polymorphism

Saliha Handan Yildiz,Alper Murat Ulaşli,Mujgan Ozdemir Erdogan,Ömer Dikici,Evrim Suna Arikan Terzi,Umit Dundar,Mustafa Solak

Assessment of Pain Sensitivity in Patients With Chronic Low Back Pain and Association With HTR2A Gene Polymorphism

2017

Saliha Handan Yildiz
Alper Murat Ulaşli
Mujgan Ozdemir Erdogan
Ömer Dikici
Evrim Suna Arikan Terzi
Umit Dundar
Mustafa Solak

Objectives This study aims to investigate the association of two common HTR2A gene polymorphisms, rs6313 (102 T/C) and rs6311 (1438 A/G), with chronic low back pain (CLBP) and the pain threshold, disability, and sex differences.

Keywords:

HTR2A gene
Threshold of pain
Polymorphism (computer science)
Serotonin
Gene polymorphism
Low back pain
Back pain
Internal medicine
Medicine
Single-nucleotide polymorphism
Rs6313
rs6311
Chronic pain

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