Determination of tauroursodeoxycholic acid in compound bile capsule by HPLC

Objective: To discriminate and determine of the artificial bear bile of the compound bile capsule. Method: Taking the pharmacopoeia as reference,the artificial bear bile was discriminated and determined by HPLC. Result: The compound bile capsule and the control sample had chromatographic peak at the same time from HPLC. The content of the artificial bear bile was above 10 mg per tablets. Conclusion: The artificial bear bile of compound bile capsules can be discriminated effectively and determined accurately by HPLC method.