[A clinical study of doxycycline slow-release gel on periodontitis chemotherapy].

Objective To observe the ef fe ct of Doxycycline slow-release on periodontitis therapy.Methods30patients with c hronic periodontitis were chosen and devided into2groups randomly,these cases we re given Doxycycline slow-re-lease and Zinciodati Comp solution.PLI,GI,SBI,P D,AL,MD and clinical syptoms were observed before and after taking drug.Result s The indose of PLI,GI,SBI,PD,AL,MD were decreased significantly after the use of Doxycycline slow-re-lease gel(P0.05),the effects of the Doxycycline was better than Zinciodati Comp solution(P0.01),no adverse drug side effects were found during trial.Conclusion The use of Doxycycline slow-release gel is one of the safe and effective chemotherapy on periodontitis.