Structure and function changes of left ventricle and the risk factors in end stage renal disease patients

Objective To investigate the changes of left ventricular structure and function and its risk factors in end stage renal disease (ESRD) patients on maintenance hemodialysis. Methods Fifty maintenance hemodialysis patients of our hospital were enrolled, and analyzed the relationship of echocardiography and blood pressure, hemoglobin, serum albumin, blood lipid , serum calcium and phosphate, PTH and uric acid. Results Forty-one patients (82%) suffered from left ventricular hypertrophy (LVH). Blood pressure, hemoglobin and PTH were significantly different between LVH and none-LVH patients(P0.05); Twelve patients characterized by left ventricular systolic dysfunction (LVSD), Serum albumin, triglyceride, calcium, uric acid, creatinine and blood nitrogen were significant- ly different between LVSD and none-LVSD patients (P 0.05); Thirty-one patients showed left ventricular diastolic dysfunction (LVDD). Blood pressure, hemoglobin and serum albumin were signtificantly different between LVDD and none-LVDD patients (P 0.05). Conclusions Abnormal left ventricularstructure and function were very popular in chronic hemodialysis ESRD patients. Our study suggests that the abnormal changes were correlated with hypertension, anemia and malnutrition.