Diastereoselective Synthesis of (E)‐1‐Trimethylsilyl‐3‐en‐1‐ynes by Palladium‐Catalyzed Cross‐Coupling Reaction between Trimethylsilylethynylzinc Chloride and Stereoisomeric Mixtures of 1‐Bromo‐1‐alkenes.

Abstract In the stereospecific palladium-catalyzed cross-coupling reaction of triimethylsilyl-ethynylzinc chloride, (B)-1-bromo-1-alkenes react preferentially in the presence of the corresponding (Z)-stereoisomers.