Problem in intrahepatic cholestasis in pregnancy

: There are observations of 37 pregnant women with cholestasis. The study of the level of bile acids, b2-microglobuline, ferritin and ultrasound echography was shown to be the most valuable diagnostic test. Absolute and relative contraindications to the maintenance of pregnancy are suggested for this group of patients. It was proved that the long-term cholemia considerably aggravates the course of the disease. The problem of the maintenance of pregnancy in each case must be solved on an individual basis and with the use of adequate therapy.