Prognostic value of semi-quantitative parameters on 18F-FDG PET/CT in patients with cardiac tumor

1352 Purpose: the aim of this study was to determine the prognostic value of semi-quantitative parameters on 18F-FDG PET/CT in patients with cardiac tumor. Methods: We performed a retrospective study including 68 patients (33men, 35women; mean age,51years; range, 18-84 years) with cardiac tumors between January 2015 and October 2019 who underwent 18F-FDG PET/CT scan prior to treatment. Maximum, mean, tumor-to-liver standardized uptake values (SUVmax, SUVavg, SUVratio[liver]), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) were obtained from 18F-FDG PET/CT. those patients were followed-up. Univariate and multivariate analyses of clinical and imaging variables were performed using the Cox proportional hazards regression analysis. Estimating the overall survival (OS) rates by Kaplan-Meier method. Survival time was defined as the time from PET/CT scan to death. Results: Median of follow-up time was 7.5 months. 25(36.8%) died during the follow-up period. Log rank test determined that the SUVmax, SUVavg, SUVratio[liver], MTV, and TLG were predicted values of OS (P < 0.05), whereas Cox regression analyses confirmed that SUVmax were independent predictor of only OS (P < 0.05). Conclusions: The SUVmax was the only independent prognostic factors for predicting OS in patients with cardiac tumor on 18F-FDG PET/CT.