Ascorbic acid 2-phosphate enhances albumin mRNA expression and secretion of porcine hepatocytes

The effect of ascorbic acid 2-phosphate (Asc2P) was tested on porcine and rat mature hepatocytes in vitro. Asc2P enhanced the porcine albumin mRNA expression. The albumin secretion released into the culture medium from the porcine hepatocytes was also increased by Asc2P. However, Asc2P did not give any effects to rat hepatocytes on albumin mRNA expression and albumin secretion. This result shows that Asc2P is one of the important factors to enhance porcine hepatocyte activity.