Abstract 221: Prognostic Impact of Estimated Glomerular Filtration Rate in Patients with Percutaneous Veno-arterial Extracorporeal Membrane Oxygenation

Purpose: Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) has been reported to improve survival in patients with cardiogenic shock or cardiac arrest. We investigated the association between initial renal function just before implantation and clinical outcome in patients undergoing VA-ECMO due to cardiogenic shock and cardiac arrest. Methods: A cohort of 212 patients (58.8±16.2 years old, 86% male) who underwent ECMO at our hospital was registered from January 2007 to December 2013. We excluded 68 patients caused by non-cardiogenic event. The remaining 144 patients (91 with acute myocardial infarction, 37 with refractory ventricular fibrillation, 6 with refractory congestive heart failure, and 6 with fulminant myocarditis) were divided into 2 groups according to initial estimated-glomerular filtration rate (eGFR). Non-CKD Group: eGFR ≥60ml/min/1.73m 2 (n=98); CKD Group: eGFR Results: The 82% of patients received VA-ECMO due to cardiac arrest. In baseline characteristics, Non-CKD group was significantly younger (50.4 vs. 62.8 years old), lower incidence of hypertension in past history (26.1 vs.52.0 %), lower BUN (13.7 vs. 24.3 mg/dl), and lower K (3.9 vs. 4.5 mEq/l, all p Conclusion: Initial low e-GFR just before implantation provides worse clinical outcome in patients with VA-ECMO due to cardiogenic shock and cardiac arrest.