Dérivation de la bile dans l'iléon terminal chez le porc : effet sur le niveau de sécrétion des acides biliaires et sur l'utilisation digestive du régime

: Bile salt output and digestive utilization of a high-lipid diet were studied in pig bile collected from the common bile duct and infused into the duodenum then into the distal ileum of the animal. Five Large-White pigs of 50 kg body-weight were fitted with three permanent fistulae, one in the common bile duct for complete collection of bile secretion, and the other two in the duodenum and the ileum (at about 80 cm from the ileo-caecal valve) for returning the secretion to the animal. The diversion of the bile into the distal ileum led to a significant 82 p. 100 decrease in daily bile acid output and a 36 p. 100 decrease in apparent digestibility of dietary energy when compared with values obtained when bile was infused into the duodenum. The latter decrease was mainly due to a marked diminution ( - 60.4 p. 100) of the digestive utilization of the dietary lipids. The results show the role of the pig small intestine in maintaining an efficient enterohepatic circulation of bile acid as a result of optimal utilization of the dietary lipids.