Community-based incidence rate of cardiovascular disease and mortality in 50–75-year-old adults

Abstract Backgrounds and objectives Updated information on the incidence of the principal cardiovascular diseases (CVDs) and cardiovascular mortality is not available in Spain. We have studied the density of the incidence of new cases of myocardial infarction, heart failure, stroke and cardiovascular mortality in adults from a population in Sanlucar de Barrameda (Spain). Materials and methods A community-based prospective follow-up study was conducted. The study enrolled 858 participants aged 50–75 years who were randomly selected from the population and followed-up for 5 years. Age and gender-adjusted incidence rates of cardiovascular disease and cardiovascular mortality were calculated, obtaining complete information for 855 participants. Prognostic risk factors of new cases of cardiovascular disease were obtained using Cox proportional hazard modeling. Results The community-based incidence rate of heart failure was 455/100,000 persons-year. The incidence of myocardial infarction, stroke and cardiovascular mortality (506, 216 and 225/100,000 persons-year, respectively) was also very elevated. Male gender, family history of early cardiovascular disease, diabetes, hypertension and sedentary life style were independent risk factors of cardiovascular disease. Conclusions The incidence of myocardial infarction in Sanlucar de Barrameda (Spain) is very high. It is the first study reported in Spain. The incidence of myocardial infarction is among the highest in Spain.