Roentgenologic Manifestations in the Lungs in Milk Allergyl1

Asyndrome of chronic recurring upper respiratory and pulmonary infections apparently associated with ingestion of milk and milk products has been described by Heiner and Sears (1). It was felt advisable to call attention to the chest involvement and its roentgenologic manifestations in this condition. Unusually high levels of precipitating antibodies to various cow's milk proteins were found by the workers cited above in the serum of infants with chronic respiratory disease. More than 2,000 patients were tested at random for the presence of these antibodies by exposing their sera to raw milk antigen by a modified double diffusion agar-in-gel technic (2). In 8 cases,3 all in infants, 5 or more precipitation bands were demonstrated and severe clinical manifestations were present. Four of the group were shown by one of us (W. T. K.) to have strongly suggestive or positive laboratory evidence of idiopathic pulmonary hemosiderosis. Clinically, the children described by Heiner and Sears had recurring or continu...