Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation

William Bracamonte-Baran,Nisha A. Gilotra,Taejoon Won,Katrina Rodriguez,Monica V. Talor,Byoung C. Oh,Jan M. Griffin,Ilan S. Wittstein,Kavita Sharma,John Skinner,Roger A. Johns,Stuart D. Russell,Robert A. Anders,Qingfeng Zhu,Marc K. Halushka,Gerald Brandacher,Daniela Cihakova

Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation

2021

William Bracamonte-Baran
Nisha A. Gilotra
Taejoon Won
Katrina Rodriguez
Monica V. Talor
Byoung C. Oh
Jan M. Griffin
Ilan S. Wittstein
Kavita Sharma
John Skinner
Roger A. Johns
Stuart D. Russell
Robert A. Anders
Qingfeng Zhu
Marc K. Halushka
Gerald Brandacher
Daniela Cihakova

Background: The role of checkpoint axes in transplantation has been partially addressed in animal models but not in humans. Occurrence of fulminant myocarditis with allorejection-like immunologic f...

Keywords:

Fulminant
Endothelium
Stromal cell
Heart transplantation
Cytotoxic T cell
Cancer research
Myocarditis
PD-L1
Transplantation
Medicine

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