Non-specific granuloma of the colon

Abstract The frequent occurrence of non-specific granulomatous inflammatory lesions of the small intestine, particularly in the ileum, is being more widely recognized, and the characteristics of these lesions are becoming better known. However, there are relatively few reported cases of granulomata in the colon, which represent the same disease, and the same pathologic process, in this lower segment of the intestinal canal. A review of the literature is presented with reference to the cases on record, and the report of an additional case is added, in which the process was located at the hepatic flexure, and which was treated by a two-stage resection of the right colon. The pathologic findings are described. Non-specific granuloma of the colon can rarely be distinguished from carcinoma either prior to, or at, operation. The indication, in either case, is for wide resection, and in the inflammatory lesions the end results are very satisfactory.