Activity of carbohydrate metabolism enzyme activity in normal and pathologic parodontal tissues

: The activity of hexokinase, glucose-6-phosphate dehydrogenase, pyruvate dehydrogenase, isocytrate dehydrogenase, alpha-ketoglutarate dehydrogenase and the ATR content in the alveolar process and gingiva of dogs are established to decrease considerably in experimental cholestasis, induced by ligation of the common bile duct. Incorporation of tissue proteins into the Krebs cycle through the reverse NAD-dependent malate dehydrogenase reaction is a compensatory reaction favouring an increase of the ATP amount in the alveolar process.