Premorbid Educational Attainment and Long-Term Motor Prognosis in Parkinson’s Disease

2021 
BACKGROUND Premorbid educational attainment is a well-known proxy of reserve, not only with regard to cognition, but also to motor symptoms. OBJECTIVE In the present study, we investigated the relationship between educational attainment and long-term motor prognosis in patients with Parkinson's disease (PD). METHODS We analyzed 466 patients with de novo PD without dementia who underwent dopamine transporter (DAT) scans and were followed up more than 2 years. Patients were divided into three groups: low education (years-of-education ≤6, n = 125), intermediate education (6 
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