Three-Component Reaction of gem-Difluorinated Cyclopropane with Alkenes and B2pin2 for the Synthesis of Monofluoroalkenes
2021
Borylative difunctionalization of alkenes has emerged as a powerful approach for synthesizing highly functionalized molecules. Herein, dual Cu/Pd-catalysed borylfluoroallylation of alkenes was smoothly achieved by using gem-difluorinated cyclopropanes and B2pin2, providing the corresponding monofluoroalkene scaffolds in moderate to high yields with excellent stereoselectivity. Moreover, an array of synthetic building blocks can be obtained by downstream transformations.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
72
References
3
Citations
NaN
KQI