Blind deconvolution in dynamic contrast-enhanced MRI and ultrasound
2014
This paper is focused on quantitative perfusion analysis using
MRI and ultrasound. In both MRI and ultrasound, most approaches
allow estimation of rate constants (Ktrans, kep for MRI) and
indices (AUC, TTP) that are only related to the physiological
perfusion parameters of a tissue (e.g. blood flow, vessel
permeability) but do not allow their absolute quantification.
Recent methods for quantification of these physiological
perfusion parameters are shortly reviewed. The main problem of
these methods is estimation of the arterial input function
(AIF). This paper summarizes and extends the current
blind-deconvolution approaches to AIF estimation. The
feasibility of these methods is shown on a small preclinical
study using both MRI and ultrasound.
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