With the introduction of a substituted or unsubstituted 4-pyridyl amino cyclic alkylthio compound

Object of the present invention is useful as a medicine is provided having introduced a substituted or unsubstituted 4-pyridyl amino novel cyclic alkylthio group or a salt thereof. According to the present invention, it may provide useful in the treatment of diseases associated with angiogenesis in the following general formula [I] or a salt thereof. By the following formula [I], the ring A represents a benzene ring or a cycloalkyl ring may be fused to an aromatic five-membered heterocyclic or six-membered heterocyclic ring, B represents an alkylene group, Rl and R2 represents H, (substituted) aryl, (substituted) heterocyclic group, R3 and R4 represent H, (substituted) alkyl, (substituted) cycloalkyl, -Z-R5, etc., R5 represents a (substituted) alkyl, (substituted) aryl group, (substituted) heterocyclic group, X and Y represents H or the like, Z represents -CO -, - COO -, - CONR6 -, - SO2-, etc., R6 represents H and the like, p represents 0, 1 or 2, q represents 0 or 1.