Coenzyme Reorientations in the Active Sites of Aspartate Aminotransferase Isoenzymes

Reorientations of the coenzyme in the active sites of aspartate aminotransferase isoenzymes have been studied by linear dichroism method. Noticeable differences in the coenzyme tilt angles have been revealed between the cytosolic and mitochondrial aspartate aminotransferases.