Synthesis and antimicrobial activity of methyl esters of 2-(het)arylamino-4-oxo-Z-2-butenoic acids, their structural analogs, and conversion products

Synthesis of a small library of compounds containing an aminovinylketone fragment is described. Results of studying their antibacterial activity against S. aureus ATCC 6538-P and E. coli ATCC 25922 are reported.