AĞIZ VE ÇENE CERRAHİSİNDE PERİOSTEUMUN GREFT OLARAK KULLANIMI: LİTERATÜR DERLEMESİ

Agiz ve cene cerrahisinde sert doku kayiplarinin onarilmasinda bircok materyal kullanilmaktadir. Kemik greftleri bu materyallerin basinda gelmekte olup, otojen, allojen, ksenojen veya alloplastik olarak siniflandirilirlar. Kemik greftlerinin osteokonduktif, osteojenik veya osteoinduktif ozellikleri, bu materyallerin kullanilmasinda ve iyilesme paterninde belirleyicidir. Periosteum; travma, tumor ve lenfosit mitojenlerin etkisiyle cogalabilmek icin uyarilabilme yetisine sahip osteoprogenitor hucreler ihtiva eden, bir kemik ortusu olarak tanimlanabilir. Yapilan bircok calismada periosteumun progenitor hucreleri sayesinde kikirdak ve kemik rejenerasyonuna katki sagladigi gosterilmistir. Bu derleme calismasinda, periosteal greftlerin osteojenik kapasitelerinin literatur isiginda aciklanmasi amaclanmistir. Anahtar kelimeler: Kemik Grefti; periosteum; kritik boyutlu defekti THE USAGE OF PERIOSTEUM AS A GRAFT MATERIAL IN ORAL AND MAXILLOFACIAL SURGERY: LITERATURE REVIEW Abstract In maxillofacial surgery, many graft materials have been used for the treatment of bony defects. Bone grafts are the main graft materials and they are classified as autogenous, allogeneic, xenogenic or alloplastic. The osteoconductive, osteogenic and osteoinductive properties of bone grafts determines the pattern of healing process and the utilization of the material. Periosteum can be defined as a bony cover that has osteoprogenitor cells with an ability of proliferation by trauma, tumor and lymphocyte mitogens. Most studies have shown  periosteum promotes the bone and cartilage tissue regeneration. The aim of this review is the investigation of osteogenic capacity of  periosteal grafts in literature. Keywords: Bone graft; periosteum; critcal size defect