Method for preparing difluoroethanol through catalytic hydrogenation
2016
The invention provides a method for preparing difluoroethanol through catalytic hydrogenation. The method has the beneficial effects that hydrogenation reduction reaction is carried out by using ethyl chlorodifluoroacetate as the raw material, a Pd/C as a catalyst, triethylanmine as an acid-binding agent and ethanol as a solvent; the atom F has higher electronegativity and HF can not be generated in the ethyl chlorodifluoroacetate hydrogenation process, but the C-Cl bond is easy to hydrogenate and HCl is easy to generate, thus neutralizing generated HCl by adding the acid-binding agent triethylanmine, propelling reaction to be carried out positively and increasing the conversion rate of ethyl chlorodifluoroacetate; on the other side, used in ester hydrogenation reaction, the Pd/C catalyst has good characteristics of low hydrogen-ester ratio, high raw material conversion rate, high alcohol selectivity, stable catalyst, and the like; and therefore, the method has the effect of solving the problems that the reaction process in the traditional ester hydrogenation process is complex, is high in investment and is not suitable for small-scale production in the fine chemical industry field.
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