Antiprotozoal polyacetylenes from the tanzanian medicinal plant Cussonia zimmermannii

From the petroleum ether extract of the root bark of Cussonia zimmermannii four polyacetylenes, 1–4, were isolated, three of which (1–3) were active against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Plasmodium falciparum, and Leishmania donovani.