In vivo evaluation of a novel format of a bivalent HER3-targeting and albumin- binding therapeutic affibody construct

Tarek Z. Bass,Maria Rosestedt,Bogdan Mitran,Fredrik Y. Frejd,John Löfblom,Vladimir Tolmachev,Stefan Ståhl,Anna Orlova

In vivo evaluation of a novel format of a bivalent HER3-targeting and albumin- binding therapeutic affibody construct

2017

Tarek Z. Bass
Maria Rosestedt
Bogdan Mitran
Fredrik Y. Frejd
John Löfblom
Vladimir Tolmachev
Stefan Ståhl
Anna Orlova

Overexpression of human epidermal growth factor receptor 3 (HER3) is involved in resistance to several therapies for malignant tumours. Currently, several anti-HER3 monoclonal antibodies are under ...

Keywords:

Human epidermal growth factor
In vivo
Bivalent (genetics)
Cancer research
Monoclonal antibody
Albumin
Chemistry
Receptor
In vitro
DOTA
Scaffold protein
Affibody molecule
Biodistribution

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations