Epidemiological study of viral diarrhea in Guangzhou.

Objective To analyze the prevalence characteristic of viral diarrhea in Guangzhou.Methods Totally 985 specimens and condition information were collected from children with acute diarrhea in Guangzhou Children's Hospital from August 2008 to July 2009,then real-time fluorescence quantitative PCR was employed to detect HRV,NORV,EAdV,ASTV and SPAV.Results Among the 985 specimens 452 specimens were positive,in which 103 specimens was found with co-infection;the annual rate of HRV,NORV,EAdV,ASTV and SPAV was 28.0%,13.7 %,8.8%,4.9% and 1.0%.About 95% of positive samples were from infants under 2 years of age;the incidence rate of watery stools,fever and vomit was 88.9%,68.4% and 75.2%.Conclusion Viral diarrhea is the most common cause in infants and young children with acute diarrhea.HRV is the most important pathogens.October to December is the peak incidence.Infants under 2 years is a major pop groups.Watery stools,fever and vomiting is infantile viral diarrhea triad.Co-infection is common but has little influence on symptoms.