Development Of Herbal Drugs In The Treatmen Of Jaundice- An Overview"

Investigation of traditional medicine is very important for the welfare of rural and tribal communities for the conventional illness. In past few decades traditional medicine has been done in India. The manifestations of liver diseases such as Hepatitis–B, including Jaundice were treating by using herbals. Alternative approaches of herbal medications are increasingly sought by jaundice patients and health care professionals. The present review aims to give data about jaundice, how it can occurs, what are the drugs causing hepatotoxicity and present trends in research of medicinal plants accrediated with anti-hepatotoxic activity. This may help to identify and develop appropriate compounds or plant products beneficial in the management of jaundice. The liver is the largest organ in the body weighing 1400-1600 gm in males and 1200-1400 gm in females. There are two main anatomical lobes- right lobe and left lobe, the right is being about six times the size of left lobe. Liver is an important organ actively involved in many metabolic functions and it is the frequent target for the number of toxicants. Hepatic damage is associated with distortion of these metabolic functions. In the absence of a reliable liver protective drugs in modern medicine, there are number of medicinal preparations in Ayurveda recommended for the treatment of liver disorders. Liver is the vital organ of metabolism, detoxification and excretion from exogenous and endogenous challenges like xenobiotics, drugs viral infections. Hepatic damage is associated with distortion of these metabolic functions. About 20,000 deaths found every year due to liver disorders 1 .