[Three-dimensional numerical simulation and hemodynamic analysis of intracranial longitypical aneurysms].

Objective To establish a model of three-dimensional numerical simulation of intracranial longitypical aneurism and analyze the hemodynamic features thereof. Methods Ten patients with intracranial longitypical aneurism underwent surgical treatment. Iutracranial vascular ultrasonography was conducted before operation. Intra-operatively three-dimensional angiography of the aneurysm was conducted and multifunctional physiological monitor was used to record the dynamic pressure and pressure wave form of the main branch parent artery. Matlab, Ansys, and Fluent softwares were used to simulate the blood flow of the longitypical aneurisms. Results The hemodynamic parameter levels were the highest at the inflow tract, followed by those at the outflow tract, and were the lowest at the top of aneurysm, for example, the blood flow velocity was (1.07 ±0.23) m/s, the dynamic pressure was (574±186) Pa, and the wall shear stress was (7.7±2.0) Pa at the inflow tract, all significantly higher than those at the top [ (0.15± 0.07) m/s, ( 37±13 ) Pa, and (0.40±0.13 ) Pa respectively, all P<0.05 ]. No eddy or just simple eddy occurred in the aneurysm. Conclusion The dynamic pressure, velocity, and wall shear stress are the lowest at the top of longitypical aneurysm which may contribute to the rupture of aneurysm. Key words: Intracranial aneurysm;  Computational fluid dynamics;  Numerical simulation