Models Derived from In Vitro Analyses of Spleen, Liver, and Lung Leukocyte Functions Predict Vaccine Efficacy against the Francisella tularensis Live Vaccine Strain (LVS)

Roberto De Pascalis,Alicia Y. Chou,Patrik Rydén,Nikki J. Kennett,Anders Sjöstedt,Karen L. Elkins

Models Derived from In Vitro Analyses of Spleen, Liver, and Lung Leukocyte Functions Predict Vaccine Efficacy against the Francisella tularensis Live Vaccine Strain (LVS)

2014

Roberto De Pascalis
Alicia Y. Chou
Patrik Rydén
Nikki J. Kennett
Anders Sjöstedt
Karen L. Elkins

Currently, there are no licensed vaccines and no correlates of protection against Francisella tularensis, which causes tularemia. We recently demonstrated that measuring in vitro control of intrama ...

Keywords:

Vaccine efficacy
Virology
Tularemia
Francisella tularensis
Spleen liver
Microbiology
Attenuated vaccine
Lung
Biology
In vitro
Strain (chemistry)
Immunology

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