Predictive value of indocyanine green clearance in acute liver failure in children: comparison with King's College and Clichy scores

Indocyanine green clearance (ICG), measured by the percentage disappearance rate (PDR), detects alterations in liver function and may be used as a noninvasive determinant of hepatic reserve in liver failure as well as a marker of graft function following liver transplantation. The administration of blood products does not interfere with the ICG-PDR as occurs with other prognostic scores (King's College and Clichy scores). The aims of this study were to compare in acute liver failure the ICG-PDR with King's College and Clichy scores and to determinate its predictive value.