The Aryl Hydrocarbon Receptor is a Repressor of Inflammation-associated Colorectal Tumorigenesis in Mouse

Objective:To determine the role of the aryl hydrocarbon receptor (AHR) in colitis-associated colorectal tumorigenesis.Background:Colorectal cancer (CRC) is the third most commonly diagnosed cancer in United States. Chronic intestinal inflammation increases the risk for the development of CRC. We inv